Metastatic Breast Cancer Presenting as Acute Appendicitis: A Rare Case Study and Review of Current Knowledge

Diagnostics (Basel). 2023 Dec 13;13(24):3657. doi: 10.3390/diagnostics13243657.

Abstract

This manuscript discusses a rare case of acute appendicitis caused by metastasis from invasive breast carcinoma of no special type in a 70-year-old female previously diagnosed with breast cancer. It delves into the diagnostic challenges and management complexities of such unusual clinical presentations. The paper includes an analysis of 19 documented cases, enriching the understanding of metastatic patterns and treatment strategies in breast cancer. It underlines the importance of considering a history of malignancy when diagnosing acute abdominal conditions and emphasizes a comprehensive approach in interpreting diagnostic imaging in patients with past oncological issues to effectively manage metastatic breast cancer exhibiting atypical manifestations.

Keywords: CDK4/6 inhibitors; acute appendicitis; clinical management; hormone therapy; immunohistochemical phenotype; invasive breast carcinoma of no special type; metastatic breast cancer; oncological diagnosis.

Publication types

  • Case Reports