Gut microbiota in women: The secret of psychological and physical well-being

World J Gastroenterol. 2023 Dec 7;29(45):5945-5952. doi: 10.3748/wjg.v29.i45.5945.

Abstract

The gut microbiota works in unison with the host, promoting its health. In particular, it has been shown to exert protective, metabolic and structural functions. Recent evidence has revealed the influence of the gut microbiota on other organs such as the central nervous system, cardiovascular and the endocrine-metabolic systems and the digestive system. The study of the gut microbiota is outlining new and broader frontiers every day and holds enormous innovation potential for the medical and pharmaceutical fields. Prevention and treatment of specific women's diseases involves the need to deepen the function of the gut as a junction organ where certain positive bacteria can be very beneficial to health. The gut microbiota is unique and dynamic at the same time, subject to external factors that can change it, and is capable of modulating itself at different stages of a woman's life, playing an important role that arises from the intertwining of biological mechanisms between the microbiota and the female genital system. The gut microbiota could play a key role in personalized medicine.

Keywords: Gut microbiota; Gut-brain axis; Health promotion; Immune system; Metabolites; Women.

Publication types

  • Editorial

MeSH terms

  • Brain
  • Central Nervous System
  • Female
  • Gastrointestinal Microbiome* / physiology
  • Humans
  • Microbiota*