Could a Gout Attack Cause Non-Arteritic Anterior Ischaemic Optic Neuropathy?

Omer Karti; Dilek Top Karti; Pelin Kiyat; Tuncer Şak

doi:10.1080/01658107.2023.2212759

Could a Gout Attack Cause Non-Arteritic Anterior Ischaemic Optic Neuropathy?

Neuroophthalmology. 2023 Jun 1;47(5-6):269-273. doi: 10.1080/01658107.2023.2212759. eCollection 2023.

Authors

Omer Karti¹, Dilek Top Karti², Pelin Kiyat¹, Tuncer Şak³

Affiliations

¹ Buca Seyfi Demirsoy Training and Research Hospital Department of Ophthalmology, İzmir Democracy University, İzmir, Türkiye.
² Department of Neurology, Bozyaka Training and Research Hospital, İzmir, Türkiye.
³ Buca Seyfi Demirsoy Training and Research Hospital Department of Rheumatology, İzmir Democracy University, İzmir, Türkiye.

Abstract

Non-arteritic anterior ischaemic optic neuropathy (NAION) is a common cause of optic neuropathy in individuals over the age of 50. While risk factors such as hypertension, diabetes, and hyperlipidaemia have been identified, recent literature suggests that new risk factors may be associated with NAION. This article reports a case of NAION that occurred concurrently with an acute gout attack in a 78-year-old male patient with no other systemic diseases. We suggest that gout may be a new potential risk factor for NAION as it has the potential to cause inflammation and vascular dysfunction, particularly during acute attacks. The case emphasises the importance of considering gout as a possible risk factor in the aetiology of NAION.

Keywords: Gout; hyperuricaemia; inflammatory arthritis; non-arteritic anterior ischaemic optic neuropathy; optic neuropathy.

Publication types

Case Reports

Grants and funding

The authors reported there is no funding associated with the work featured in this article.