Robustness and complexity

Steven A Frank

doi:10.1016/j.cels.2023.11.003

Robustness and complexity

Cell Syst. 2023 Dec 20;14(12):1015-1020. doi: 10.1016/j.cels.2023.11.003.

Author

Steven A Frank¹

Affiliation

¹ Department of Ecology and Evolutionary Biology, University of California, Irvine, Irvine, CA 92697-2525, USA. Electronic address: safrank@uci.edu.

PMID: 38128480
DOI: 10.1016/j.cels.2023.11.003

Abstract

When a system robustly corrects component-level errors, the direct pressure on component performance declines. Components become less reliable, maintain more genetic variability, or drift neutrally, creating new forms of complexity. Examples include the hourglass pattern of biological development and the hourglass architecture for robustly complex systems in engineering.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Cell Biology*