Neurosurgery elucidates somatic mutations

Science. 2023 Dec 22;382(6677):1360-1362. doi: 10.1126/science.adj2244. Epub 2023 Dec 21.

Eduardo A Maury^{1

2

3}, Christopher A Walsh^{1

3

4}, Kristopher T Kahle^{1

5

6

7}

¹ Division of Genetics and Genomics, Manton Center for Orphan Disease, Boston Children's Hospital, Boston, MA, USA.
² Harvard/MIT MD-PhD Program, Harvard Medical School, Boston, MA, USA.
³ Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
⁴ Howard Hughes Medical Institute, Boston Children's Hospital, Boston, MA, USA.
⁵ Program in Neuroscience, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
⁶ Department of Neurosurgery, Boston Children's Hospital, Boston, MA, USA.
⁷ Department of Neurosurgery, Massachusetts General Hospital, Boston, MA, USA.

Abstract

Surgical innovation is helping to identify roles for somatic mutations in brain disorders.