Few-shot EEG sleep staging based on transductive prototype optimization network

Front Neuroinform. 2023 Dec 6:17:1297874. doi: 10.3389/fninf.2023.1297874. eCollection 2023.

Abstract

Electroencephalography (EEG) is a commonly used technology for monitoring brain activities and diagnosing sleep disorders. Clinically, doctors need to manually stage sleep based on EEG signals, which is a time-consuming and laborious task. In this study, we propose a few-shot EEG sleep staging termed transductive prototype optimization network (TPON) method, which aims to improve the performance of EEG sleep staging. Compared with traditional deep learning methods, TPON uses a meta-learning algorithm, which generalizes the classifier to new classes that are not visible in the training set, and only have a few examples for each new class. We learn the prototypes of existing objects through meta-training, and capture the sleep features of new objects through the "learn to learn" method of meta-learning. The prototype distribution of the class is optimized and captured by using support set and unlabeled high confidence samples to increase the authenticity of the prototype. Compared with traditional prototype networks, TPON can effectively solve too few samples in few-shot learning and improve the matching degree of prototypes in prototype network. The experimental results on the public SleepEDF-2013 dataset show that the proposed algorithm outperform than most advanced algorithms in the overall performance. In addition, we experimentally demonstrate the feasibility of cross-channel recognition, which indicates that there are many similar sleep EEG features between different channels. In future research, we can further explore the common features among different channels and investigate the combination of universal features in sleep EEG. Overall, our method achieves high accuracy in sleep stage classification, demonstrating the effectiveness of this approach and its potential applications in other medical fields.

Keywords: EEG; few-shot; meta-learning; sleep stage; transductive prototype optimization.

Grants and funding

This work was supported by the STI 2030-Major Projects 2022ZD0208900, the National Natural Science Foundation of China (Grant Nos. 62006082 and 61906019), the Key Realm R and D Program of Guangzhou (Grant No. 202007030005), and the Guangdong Basic and Applied Basic Research Foundation (Grant Nos. 2021A1515011600, 2020A1515110294, and 2021A1515011853).