[Analysis of the prevalence of dyslipidemia and correlative factors in Tajik population in Pamir Plateau of Xinjiang]

Zhonghua Xin Xue Guan Bing Za Zhi. 2023 Dec 24;51(12):1240-1246. doi: 10.3760/cma.j.cn112148-20231007-00231.
[Article in Chinese]

Abstract

Objective: To investigate the prevalence of dyslipidemia and the level of blood lipids among Tajik people in Pamir Plateau, Xinjiang, and explore the related factors of dyslipidemia. Methods: It is a retrospective cross-sectional study. A multi-stage cluster random sampling survey was conducted among 5 635 Tajiks over 18 years old in Tashkorgan Tajik Autonomous County, Xinjiang Province from May to October 2021. Data were collected through questionnaire survey (general information, medical history, and personal history), physical examination (height, weight, waist, and blood pressure) and blood test (total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), and high-density cholesterol (HDL-C)) to analyze the dyslipidemia and its risk factors among Tajiks. Results: The age of Tajik participants was (41.9±15.0) years, including 2 726 males (48.4%). The prevalence of borderline high TC, high LDL-C and high TG levels were 17.2%, 14.7% and 8.9%, respectively. The prevalence of high TC, high LDL-C, high TG and low HDL-C were 4.1%, 4.9%, 9.4% and 32.4%, respectively, and the prevalence of dyslipidemia was 37.0%. There is a positive correlation between male,higher education level, higher body mass index (BMI) value,waist circumference, living in town, smoking and dyslipidemia. Conclusions: The low prevalence of high TC, high LDL-C, high TG and high prevalence of low HDL-C was a major characteristic of Tajik people in Pamir Plateau of Xinjiang. The lower rates of overweight and obesity may be one of the reasons for the lower prevalence of dyslipidemia among Tajik.

目的: 了解新疆帕米尔高原塔吉克族血脂水平及血脂异常流行情况,探索血脂异常的相关因素。 方法: 本研究为横断面研究。于2021年5至10月在新疆塔什库尔干塔吉克自治县采用多阶段整群随机抽样调查了5 635名18岁以上塔吉克族,收集问卷调查(一般信息、疾病史、个人史等)、体格检查(身高、体重、腰围、血压等)和血液标本检测数据[总胆固醇(TC),甘油三酯(TG),低密度脂蛋白胆固醇(LDL-C),高密度脂蛋白胆固醇(HDL-C)等],分析塔吉克族血脂异常患病情况及相关因素。 结果: 塔吉克族研究对象年龄(41.9±15.0)岁,男性2 726人(48.4%)。TC、LDL-C、TG水平边缘升高患病率分别为17.2%、14.7%、8.9%。高TC血症、高LDL-C血症、高TG血症、低HDL-C血症患病率分别为4.1%、4.9%、9.4%、32.4%,血脂异常患病率为37.0%。男性、更高的文化程度、更大的体重指数和腰围、生活在城镇、吸烟是血脂异常的正相关因素。 结论: 新疆帕米尔高原塔吉克族血脂异常患病情况以较低的高TC、高LDL-C和高TG血症患病率和较高的低HDL-C血症患病率为主要特点。较低的超重和肥胖率可能是塔吉克族血脂异常患病率较低的原因之一。.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Cholesterol
  • Cholesterol, HDL
  • Cholesterol, LDL
  • Cross-Sectional Studies
  • Dyslipidemias* / epidemiology
  • Female
  • Humans
  • Hypercholesterolemia* / epidemiology
  • Hypertriglyceridemia* / epidemiology
  • Male
  • Middle Aged
  • Prevalence
  • Retrospective Studies

Substances

  • Cholesterol
  • Cholesterol, HDL
  • Cholesterol, LDL

Supplementary concepts

  • Tajik people