Multicolor imaging: Current clinical applications

Surv Ophthalmol. 2024 May-Jun;69(3):378-402. doi: 10.1016/j.survophthal.2023.11.011. Epub 2023 Dec 19.

Abstract

Multicolor (MC) imaging is an innovative pseudocolor fundus imaging modality based on confocal scanning laser ophthalmoscopy. It effectively scans the retina at different depths to create a composite image. The green reflectance image depicts the middle retinal while blue reflectance image provides images of the retinal surface. The infrared reflectance image depicts retinal structures at the level of outer retina and choroid. We systematically analyze published case reports, case series, and original articles on MC imaging where it has helped in discovering additional clinical features of retinal diseases not readily apparent on conventional color fundus photography and played a role in monitoring the response to treatment.

Keywords: Blue reflectance; Green reflectance; Infrared reflectance; Multicolour imaging.

Publication types

  • Review

MeSH terms

  • Fluorescein Angiography / methods
  • Fundus Oculi
  • Humans
  • Ophthalmoscopy* / methods
  • Retina / diagnostic imaging
  • Retina / pathology
  • Retinal Diseases* / diagnosis
  • Retinal Diseases* / diagnostic imaging