Thymic Carcinoid in a Patient with Concurrent Manifestations of Multiple Endocrine Neoplasia Type 1

Jasmine Zhu; Samantha Dean; Umbreen Hafeez; Sandra Neoh

doi:10.1155/2023/8801080

Thymic Carcinoid in a Patient with Concurrent Manifestations of Multiple Endocrine Neoplasia Type 1

Case Rep Endocrinol. 2023 Dec 11:2023:8801080. doi: 10.1155/2023/8801080. eCollection 2023.

Authors

Jasmine Zhu^{1

2}, Samantha Dean³, Umbreen Hafeez^{2

3

4}, Sandra Neoh¹

Affiliations

¹ Department of Endocrinology, Austin Health, 145 Studley Rd, Heidelberg, VIC 3084, Australia.
² Melbourne Medical School, University of Melbourne, Parkville, VIC 3010, Australia.
³ Department of Oncology, Austin Health, 145 Studley Rd, Heidelberg, VIC 3084, Australia.
⁴ School of Cancer Medicine, La Trobe University, Plenty Road and Kingsbury Dr, Bundoora, VIC 3086, Australia.

Abstract

Thymic carcinoid tumours, especially in the context of multiple endocrine neoplasia type 1 (MEN 1), present significant clinical challenges due to their rarity and aggressive nature. This case report describes a complex patient with MEN 1, who suffered from multiple manifestations of the disease, including thymic carcinoid. The tumour was initially resected and treated with adjuvant radiotherapy. Due to slow progression over the years, the tumour was treated with two lines of chemotherapy before the patient succumbed to progressive disease. There is currently limited evidence favoring any specific medical treatment for thymic carcinoid.

Publication types

Case Reports