Objective:To explore the clinical manifestations,the type of pathology, treatment and prognosis of laryngeal rhabdomyosarcoma, and to enhance the understanding of the clinical characteristics of the disease, while improving the diagnosis rateand reducing the misdiagnosis rate, in order to explore effective diagnosis and treatment methods. Methods:A retrospective analysis was conducted on the clinical data of 5 cases of laryngeal rhabdomyosarcoma treated in the First Affiliated Hospital of Zhengzhou University from May 2015 to May 2021. Results:All 5 cases of laryngeal rhabdomyosarcoma were misdiagnosed in the early stage. with tumors mostly occurring in the vocal cords and appearing as smooth mass. The clinical symptoms were mostly hoarseness. According to pathological classification, three cases were embryonic type, one case was polymorphic type, and one case was spindle type.Three patients died due to tumor recurrence, one patient had multiple systemic metastases, and another patient who underwent surgical resection in the early stage and supplemented with postoperative radiotherapy and chemotherapyhas been followed up to date without recurrence. Conclusion:Laryngeal rhabdomyosarcoma has low incidence rate, high malignancy degree and poor prognosis. It is easy to be misdiagnosed as a benign mass. Extensive surgical resection combined with radiotherapy and chemotherapy should be performed as soon as possible after diagnosis.
目的：探讨喉部横纹肌肉瘤（rhabdomyosarcoma，RMS）的临床表现、病理类型、治疗及预后，提高对该病临床特点的认识，提高诊断率，降低误诊率，探讨有效的诊治方法。 方法：回顾性分析2015年5月—2021年5月郑州大学第一附属医院收治的5例喉RMS的临床及随访资料。 结果：5例喉部RMS早期均被误诊，多发生在声带，肉眼观为光滑的肿块，多表现为声嘶。3例为胚胎型，1例多形型，1例梭形型。除早期行手术切除并术后辅以放化疗的患者随访至今无复发，3例因肿瘤复发死亡，1例肿瘤全身多处转移。 结论：喉RMS发病率低，恶性程度高、预后差，易被误诊为良性肿块，确诊后尽早行扩大范围的手术切除并辅以放化疗。.
Keywords: laryngeal neoplasms; prognosis; rhabdomyosarcoma; treatment.
Copyright© by the Editorial Department of Journal of Clinical Otorhinolaryngology Head and Neck Surgery.