Tapentadol dependence through intravenous injection ('shooting') of crushed tablets associated with cutaneous pseudoallergic reactions

BMJ Case Rep. 2023 Dec 19;16(12):e257721. doi: 10.1136/bcr-2023-257721.

Abstract

Tapentadol is a synthetic opioid analgesic with a low risk of abuse and diversion. The rising trend of abuse of tapentadol is largely attributable to its intrinsic pharmacological profile and easy availability due to poor regulatory control. We report a case of intravenous injection of crushed tapentadol tablets that presented with cutaneous adverse drug reactions. Cutaneous adverse reactions are common in injection drug abuse, and clinical examination is a must to inspect the injection sites. Stringent regulatory measures are required to restrict the increasing abuse of tapentadol in India.

Keywords: Drugs misuse (including addiction); Unwanted effects / adverse reactions.

Publication types

  • Case Reports

MeSH terms

  • Analgesics, Opioid* / administration & dosage
  • Analgesics, Opioid* / adverse effects
  • Humans
  • Injections, Intravenous
  • Tablets
  • Tapentadol* / administration & dosage
  • Tapentadol* / adverse effects

Substances

  • Analgesics, Opioid
  • Tablets
  • Tapentadol