Development of Flexible Medical Electrodes Using Carrageenan-Based Bioplastics with the Addition of Conductive Hybrid Materials Graphite and Silver Nanoparticles

Fathur Rahman; Damar Rastri Adhika; Akhmad Zein Eko Mustofa; Suprijanto

doi:10.1021/acsomega.3c06987

Development of Flexible Medical Electrodes Using Carrageenan-Based Bioplastics with the Addition of Conductive Hybrid Materials Graphite and Silver Nanoparticles

ACS Omega. 2023 Dec 4;8(49):47086-47099. doi: 10.1021/acsomega.3c06987. eCollection 2023 Dec 12.

Authors

Fathur Rahman¹, Damar Rastri Adhika^{2

3}, Akhmad Zein Eko Mustofa³, Suprijanto⁴

Affiliations

¹ Magister of Nanoscience and Nanotechnology, Graduate School, ITB, Jl. Ganesa No. 10, Bandung 40132, Indonesia.
² Advanced Functional Materials Research Group, Faculty of Industrial Technology, Institut Teknologi Bandung, Jl. Ganesa No. 10, Bandung 40132, Indonesia.
³ Research Center for Nanoscience and Nanotechnology, ITB, Jl. Ganesa No. 10, Bandung 40132, Indonesia.
⁴ Instrumentation and Control Research Group, Faculty of Industrial Technology, ITB, Jl. Ganesa No. 10, Bandung 40132, Indonesia.

Abstract

Electrodes are crucial in medical devices, specifically health monitoring devices for biopotential measurements such as electrocardiography, electromyography (EMG), and electroencephalography. The commonly used rigid electrodes have limitations in their skin-electrode contact quality since they cannot conform to the skin's surface area and body contours. Flexible electrodes have been developed to better conform to the body's surface contours, improving ion transfer and minimizing motion artifacts, thereby enhancing the signal-to-noise ratio (SNR). Bioplastic substrates based on carrageenan have been chosen for their safety, abundance, flexibility, and ease of customization. Hybrid materials of graphite and silver nanoparticles (graphite-AgNPs) exhibit high electron capacitance, low charge transfer resistance, and superior surface catalytic activity. These make them ideal as conductive fillers for bioplastics to achieve good electrical characteristics as electrodes. The effect of the graphite-AgNP filler concentration, graphite particle size, and flexible electrode thickness was evaluated to assess their impact on the electrical and mechanical properties of the fabricated flexible electrodes. The graphite-AgNP fillers were incorporated into a bioplastic matrix, resulting in flexible electrodes with improved conductivity with increasing percentages of graphite-AgNP at the expense of flexibility. The thickness of the flexible electrode was varied to evaluate its effect on the conductivity. A graphite size reduction was performed to improve the electrical properties while maintaining the mechanical properties. The most optimal variation of flexible electrodes with desirable electrical and mechanical properties was achieved by adding 25% graphite-AgNP to the carrageenan, using graphite particles of 400-700 nm, and using the thinnest electrode. The optimized electrode also exhibited an improved SNR value in EMG signal measurements compared to conventional Ag/AgCl electrodes. This research presents a novel approach to developing environmentally friendly, customizable, and flexible electrodes for medical applications.