Many instruments for astroparticle physics are primarily geared towards multi-messenger astrophysics, to study the origin of cosmic rays and to understand high-energy astrophysical processes. Since these instruments observe the Universe at extreme energies and in kinematic ranges not accessible at accelerators these experiments provide also unique and complementary opportunities to search for particles and physics beyond the standard model of particle physics. In particular, the reach of IceCube, Fermi and KATRIN to search for and constrain Dark Matter, Axions, heavy Big Bang relics, sterile neutrinos and Lorentz invariance violation will be discussed. The contents of this article are based on material presented at the Humboldt-Kolleg 'Clues to a mysterious Universe-exploring the interface of particle, gravity and quantum physics' in June 2022. This article is part of the theme issue 'The particle-gravity frontier'.
Keywords: beyond-standard-model physics; gamma rays; neutrinos.