Preoperative Risk Factors and Postoperative Complications of COVID-Positive Children Requiring Urgent or Emergent Surgical Care

Kendall Gross; Christina Georgeades; Carisa Bergner; Kyle J Van Arendonk; Jose H Salazar

doi:10.1016/j.jpedsurg.2023.11.007

Preoperative Risk Factors and Postoperative Complications of COVID-Positive Children Requiring Urgent or Emergent Surgical Care

J Pediatr Surg. 2024 Apr;59(4):686-693. doi: 10.1016/j.jpedsurg.2023.11.007. Epub 2023 Nov 21.

Authors

Kendall Gross¹, Christina Georgeades¹, Carisa Bergner¹, Kyle J Van Arendonk¹, Jose H Salazar²

Affiliations

¹ Division of Pediatric Surgery, Children's Wisconsin and Medical College of Wisconsin, 999 N 92nd Street, Suite 320, Milwaukee, WI, 53226, USA.
² Division of Pediatric Surgery, Children's Wisconsin and Medical College of Wisconsin, 999 N 92nd Street, Suite 320, Milwaukee, WI, 53226, USA. Electronic address: jsalazar@childrenswi.org.

PMID: 38104034
DOI: 10.1016/j.jpedsurg.2023.11.007

Abstract

Background: Preoperative COVID-19 testing protocols were widely implemented for children requiring surgery, leading to increased resource consumption and many delayed or canceled operations or procedures. This study using multi-center data investigated the relationship between preoperative risk factors, COVID-positivity, and postoperative outcomes among children undergoing common urgent and emergent procedures.

Methods: Children (<18 years) who underwent common urgent and emergent procedures were identified in the 2021 National Surgical Quality Improvement Program Pediatric database. The outcomes of COVID-positive and non-COVID-positive (negative or untested) children were compared using simple and multivariable regression models.

Results: Among 40,628 children undergoing gastrointestinal surgery (appendectomy, cholecystectomy), long bone fracture fixation, cerebrospinal fluid shunt procedures, gonadal procedures (testicular detorsion, ovarian procedures), and pyloromyotomy, 576 (1.4%) were COVID-positive. COVID-positive children had higher American Society of Anesthesiologists scores (p ≤ 0.001) and more frequently had preoperative sepsis (p ≤ 0.016) compared to non-COVID-positive children; however, other preoperative risk factors, including comorbidities, were largely similar. COVID-positive children had a longer length of stay than non-COVID-positive children (median 1.0 [IQR 0.0-2.0] vs. 1.0 [IQR 0.0-1.0], p < 0.001). However, there were no associations between COVID-19 positivity and overall complications, pulmonary complications, infectious complications, or readmissions.

Conclusions: Despite increased preoperative risk factors, COVID-positive children did not have an increased risk of postoperative complications after common urgent and emergent procedures. However, length of stay was greater for COVID-positive children, likely due to delays in surgery related to COVID-19 protocols. These findings may be applicable to future preoperative testing and surgical timing guidelines related to respiratory viral illnesses in children.

Level of evidence: III.

Keywords: COVID-19; Pediatric surgery; Postoperative complications; Preoperative risk factors.

MeSH terms

COVID-19 Testing*
COVID-19* / complications
COVID-19* / epidemiology
Child
Humans
Patient Readmission
Postoperative Complications / epidemiology
Postoperative Complications / etiology
Retrospective Studies
Risk Factors