The Influence of Titanium-coated Poryetheretherketone Cages in Fusion Status after Posterior Lumbar Interbody Fusion with Cortical Bone Trajectory Screw Fixation

World Neurosurg. 2024 Mar:183:e201-e209. doi: 10.1016/j.wneu.2023.12.056. Epub 2023 Dec 13.

Abstract

Objective: Posterior lumbar interbody fusion (PLIF) with cortical bone trajectory (CBT) screw fixation (CBT-PLIF) shows potential for reducing adjacent segmental disease. Previously, our investigations revealed a relatively lower fusion rate with the use of carbon fiber-reinforced polyetheretherketone (CP) cages in CBT-PLIF compared with traditional pedicle screw fixation (PS-PLIF) using CP cages. This study aims to evaluate whether the implementation of titanium-coated polyetheretherketone (TP) cages can enhance fusion outcomes in CBT-PLIF.

Methods: A retrospective analysis was conducted on 68 consecutive patients who underwent CBT-PLIF with TP cages (TP group) and 89 patients who underwent CBT-PLIF with CP cages (CP group). Fusion status was assessed using computed tomography at 1 year postoperatively and dynamic plain radiographs at 2 years postoperatively.

Results: No statistically significant differences in fusion rates were observed at 1 and 2 years postoperatively between the TP group (86.8% and 89.7%, respectively) and the CP group (77.5% and 88.8%, respectively). Notably, the CP group exhibited a significant improvement in fusion rate from 1 to 2 years postoperatively (P = 0.002), while no significant improvement was observed in the TP group.

Conclusions: Examination of temporal changes in fusion rates reveals that only the TP group achieved a peak fusion rate 1 year postoperatively. This implies that TP cages may enhance the fusion process even after CBT-PLIF. Nevertheless, the definitive efficacy of TP cages for CBT-PLIF remains uncertain in the context of overall fusion rates.

Keywords: Cortical bone trajectory screw; Lumbar degenerative disease; Posterior lumbar interbody fusion; Titanium-coated PEEK cage.

MeSH terms

  • Benzophenones*
  • Cortical Bone / diagnostic imaging
  • Cortical Bone / surgery
  • Humans
  • Ketones
  • Lumbar Vertebrae / diagnostic imaging
  • Lumbar Vertebrae / surgery
  • Pedicle Screws*
  • Polyethylene Glycols
  • Polymers*
  • Retrospective Studies
  • Spinal Fusion* / methods
  • Titanium
  • Treatment Outcome

Substances

  • polyetheretherketone
  • Titanium
  • Polyethylene Glycols
  • Ketones
  • Benzophenones
  • Polymers