Two Mo-Ti-mixed oxide clusters, Ti6Mo4 and Ti4Mo4, which contain the {Mo2V} unit commonly observed in many polyoxomolybdates, were successfully synthesized. The introduction of a {Mo2V} dopant into a titanium-oxide cluster (TOC) results in a red shift of the absorption edge, hence leading to a substantial enhancement of visible-light absorption. The band gap electron transition mainly involves the ligand-to-metal charge transfer (LMCT, benzoate-to-Mo) and MoV d-d transition. Both clusters show favorable visible-light responsiveness and charge-separation efficiency. Both serve as heterogeneous photocatalysts and exhibit excellent catalytic activity in CO2/epoxide cycloadditions under very mild conditions. The mechanism study suggests that the catalytically active sites are mainly MoV, and the photogenerated electrons and holes are both involved. Ti6Mo4 exhibits better photocatalytic activity than Ti4Mo4, demonstrating the crucial role of the titanium-oxide core, which corresponds to improved light absorption and charge-separation efficiency. Our findings highlight the potential of the {Mo2V} unit in constructing Mo-Ti-mixed oxide clusters with interesting topologies and excellent solar-light-harvesting activity.