Management of anesthesia in pregnant women with pulmonary hypertension

Eur Rev Med Pharmacol Sci. 2023 Dec;27(23):11315-11322. doi: 10.26355/eurrev_202312_34570.

Abstract

Objective: Pulmonary hypertension (PH) is a rare heart disease associated with high maternal and fetal mortality. This study aims to discuss anesthesia management and the fetal and maternal outcomes of patients with PH followed-up at our clinic.

Patients and methods: This study includes a retrospective analysis of 105 pregnant women with PH. The patients were classified according to the mean pulmonary artery pressure (mPAP) values measured at rest by transthoracic echocardiography. The first group included patients with an mPAP value between 25 and 49 mmHg, considered to have a mild PH, whereas patients with an mPAB value ≥50 mmHg were considered to have severe PH and were included in the second group.

Results: When the patients were examined for etiology, the majority (n=84, 70.5%) were found to have type 2 PH. It was found that in pregnant women with severe PH, the diameters of the left atrium, right atrium, and right ventricle were significantly larger (p=0.008, p=0.04, and p=0.013, respectively), and the ejection fraction was also significantly lower (p=0.04).

Conclusions: Although there has been a partial decrease in mortality for PH in recent years, it is still a serious condition that requires a multidisciplinary approach and well-planned obstetric treatment.

MeSH terms

  • Anesthesia*
  • Echocardiography
  • Female
  • Humans
  • Hypertension, Pulmonary*
  • Pregnancy
  • Pregnant Women
  • Retrospective Studies