Lymphocyte and neutrophil count combined with intestinal bacteria abundance predict the severity of COVID-19

Microbiol Spectr. 2024 Jan 11;12(1):e0302723. doi: 10.1128/spectrum.03027-23. Epub 2023 Dec 13.

Abstract

The 2019 coronavirus disease (COVID-19) patients had a unique profile of gut bacteria. In this study, we characterized the intestinal bacteria in our COVID-19 cohorts and found that there was an increased incidence of severe cases in COVID-19 patients with decreased lymphocytes and increased neutrophils. Levels of lymphocytes and neutrophils and abundances of intestinal bacteria correlated with the severity of COVID-19.

Keywords: COVID-19; bacteria; lymphocytes; neutrophils.

MeSH terms

  • COVID-19*
  • Humans
  • Lymphocyte Count
  • Lymphocytes
  • Neutrophils*
  • SARS-CoV-2