Association of fresh vegetable and salt-preserved vegetable consumptions with estimated glomerular filtration rate

BMC Nephrol. 2023 Dec 12;24(1):369. doi: 10.1186/s12882-023-03353-5.

Abstract

Objective: This study aimed to investigate the relationship between the consumption of fresh and salt-preserved vegetables and the estimated glomerular filtration rate (eGFR), which requires further research.

Methods: For this purpose, the data of those subjects who participated in the 2011-2012 and 2014 surveys of the Chinese Longitudinal Healthy Longevity Survey (CLHLS) and had biomarker data were selected. Fresh and salt-preserved vegetable consumptions were assessed at each wave. eGFR was assessed using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation based on plasma creatinine. Furthermore, a linear mixed model was used to evaluate associations between fresh/salt-preserved vegetables and eGFR.

Results: The results indicated that the median baseline and follow-up eGFRs were 72.47 mL/min/1.73 m² and 70.26 mL/min/1.73 m², respectively. After applying adjusted linear mixed model analysis to the data, the results revealed that compared to almost daily intake, occasional consumption of fresh vegetables was associated with a lower eGFR (β=-2.23, 95% CI: -4.23, -0.23). Moreover, rare or no consumption of salt-preserved vegetables was associated with a higher eGFR (β = 1.87, 95% CI: 0.12, 3.63) compared to individuals who consumed salt-preserved vegetables daily.

Conclusion: Fresh vegetable consumption was direct, whereas intake of salt-preserved vegetables was inversely associated with eGFR among the oldest subjects, supporting the potential benefits of diet-rich fresh vegetables for improving eGFR.

Keywords: Association; Estimated glomerular filtration rate; Fresh vegetables; Oldest subjects; Salt-preserved vegetables.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Creatinine
  • Glomerular Filtration Rate
  • Humans
  • Kidney Function Tests
  • Longitudinal Studies
  • Renal Insufficiency, Chronic* / epidemiology
  • Sodium Chloride, Dietary
  • Vegetables*

Substances

  • Sodium Chloride, Dietary
  • Creatinine