[In Vitro Degradation Behavior of Absorbable Interface Screws]

Zhongguo Yi Liao Qi Xie Za Zhi. 2023 Nov 30;47(6):598-601. doi: 10.3969/j.issn.1671-7104.2023.06.002.
[Article in Chinese]

Abstract

The composite material PLGA compounded with β-tricalcium phosphate (β-TCP) was prepared by melt blending method, and the absorbable interface screw was prepared by injection molding process. Prepare PBS buffer that simulates human body, conduct in vitro degradation experiments on interface screws according to relevant national and industry standards, then test and characterize interface screws at different time points for degradation of intrinsic viscosity, average molecular weight distribution, mass loss, mechanical properties and thermal properties. According to the degradation performance-time curve, determine the time node at which the interface screw loses the mechanical properties. In this paper, the in vitro degradation behavior of interfacial screws prepared from PLGA and β-TCP composites was studied in detail, providing a reference and basis for the degradation behavior of absorbable products prepared from PLGA and β-TCP composites.

Keywords: absorbable; in vitro degradation; interface screw; performance study.

Publication types

  • English Abstract

MeSH terms

  • Absorbable Implants
  • Calcium Phosphates*
  • Humans
  • Materials Testing
  • Polyesters*

Substances

  • beta-tricalcium phosphate
  • Polyesters
  • Calcium Phosphates