The Pragmatism of Polyphenols and Flavonoids Application as Drugs, from an Academic Lab to a Pharmacy Shelf

Curr Pharm Des. 2023;29(43):3421-3427. doi: 10.2174/0113816128273103231204064507.

Abstract

Polyphenols and flavonoids, naturally occurring compounds found abundantly in plants, have gained considerable attention in recent years due to their potential health benefits. Research exploring their bioactive properties has revealed promising therapeutic applications in various diseases. This article aims to provide a comprehensive overview of the intricate journey from academic laboratory discoveries to the availability of polyphenols and flavonoids as drugs on pharmacy shelves. It was shown that the transformation of these natural compounds into effective therapies is a promising avenue for enhancing human health. Yet, fully realizing this potential necessitates sustained scientific exploration, cross-disciplinary collaboration, and continued investment in research and development. This article underscores the importance of sustained collaboration and investment as key pillars of progress towards innovative and effective therapies.

Keywords: Noncommunicable disease; cancer; flavonoids; health benefits.; natural medicines; polyphenols.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Flavonoids* / pharmacology
  • Flavonoids* / therapeutic use
  • Humans
  • Pharmacy*
  • Polyphenols / pharmacology

Substances

  • Flavonoids
  • Polyphenols