Safety and Efficacy of Endovascular Coils and Non-Flow-Diverting Stents for Management of Unruptured Intracranial Aneurysms: A Location-Specific Outcomes Analysis

World Neurosurg. 2024 Feb:182:e734-e741. doi: 10.1016/j.wneu.2023.12.028. Epub 2023 Dec 10.

Abstract

Introduction: The relationship between the anatomical location of an unruptured saccular aneurysm, the efficacy, and the potential complications associated with coil and non-flow-diverting stents remains poorly documented. Therefore, the aim of this study is to evaluate the efficacy and safety of endovascular treatment based on the anatomical position of the unruptured intracranial aneurysm (UIA).

Methods: A retrospective cohort study was conducted using an anonymized database of patients who underwent endovascular therapy for UIAs between 2014 and 2021.

Results: A total of 138 patients with 147 UIAs were included. Immediate Raymond-Roy occlusion class I or II was achieved in 99.2% of patients in all anatomical locations, with a 96.2% occlusion rate at the 12-month follow-up. Complications occurred more frequently in the anterior cerebral artery (35%) and internal carotid artery in its ophthalmic segment (25%). However, the difference was not statistically significant.

Conclusions: Our study shows that endovascular treatment with stents and coils is effective and safe for managing UIAs in various anatomical locations. The incidence of thromboembolic complications was significantly higher for UIAs located in the anterior cerebral artery.

Keywords: Complications; Endovascular; Intracranial aneurysm; Procedures; Stents.

MeSH terms

  • Embolization, Therapeutic* / adverse effects
  • Endovascular Procedures* / adverse effects
  • Humans
  • Intracranial Aneurysm* / complications
  • Retrospective Studies
  • Stents / adverse effects
  • Treatment Outcome