Comparison of drug concentrations in blood and gastric lavage fluid before and after gastric lavage: A case report

World J Clin Cases. 2023 Nov 6;11(31):7680-7683. doi: 10.12998/wjcc.v11.i31.7680.

Abstract

Background: Gastric lavage (GL) is one of the most important early therapies to remove unabsorbed toxins from the gastrointestinal tract. However, the details of performing gastric lavage remain to be established. There is controversy in clinical practice regarding individual choice of the timing of GL and its efficiency.

Case summary: We report the case of a young woman who presented to the Emergency Department with drug intoxication for four hours. We used the latest toxicological screening techniques to compare drug concentrations in the patient's blood and gastric lavage fluid before and after gastric lavage. The results confirmed that gastric lavage was effective in reducing drug concentrations in the stomach; a small amount of drug remained in the stomach at the end of gastric lavage.

Conclusion: Gastric lavage is effective in reducing drug concentrations in the stomach, with a small amount of drug remaining in the stomach at the end of gastric lavage.

Keywords: Case report; Drug concentrations; Gastric lavage; Oral poisoning.

Publication types

  • Case Reports