Therapeutic efficacy of optimal pulse technology in the treatment of chalazions

Xi Song; Chunying Zhang; Saisai Zhang; Mansha He

doi:10.3389/fmed.2023.1286159

Therapeutic efficacy of optimal pulse technology in the treatment of chalazions

Front Med (Lausanne). 2023 Nov 21:10:1286159. doi: 10.3389/fmed.2023.1286159. eCollection 2023.

Authors

Xi Song¹, Chunying Zhang¹, Saisai Zhang¹, Mansha He¹

Affiliation

¹ Guangzhou Aier Eye Hospital Affiliated to Jinan University, Guangzhou, Guangdong, China.

Abstract

Introduction: To evaluate the efficacy of optimized pulse technology in treating chalazia.

Methods: Prospective before-after study. All patients received two sessions of optimal pulse technology (OPT) with an interval of 1 week. The first visit was before treatment and the patients underwent 2 treatment sessions with a 1-week interval. The non-invasive tear breakup time (NIBUT), corneal fluorescein staining (CFS) score, Schirmer's test I without anesthesia, conjunctival hyperemia, and meibomian gland area were compared before and after treatment, and the related factors of curative effect were analyzed.

Results: 23 patients (23 eyes) with chalazia were included. All patients received two sessions of OPT treatment at 1-week intervals. Following the first OPT treatment, a reduction in the chalazion size was observed in 17 patients (73.91%). One patient was completely cured, and 1 patient had an increase in the diameter of the chalazion. The meibomian gland area increased significantly compared to before treatment (p = 0.023). Compared with baseline, the conjunctival congestion and ST decreased, NIBUT increased, and there was no statistical difference. After the second treatment, the chalazion size decreased in 21 cases, and 3 patients were cured. A significant increase in the meibomian gland area compared with the baseline area (p < 0.001). Additionally, conjunctival congestion decreased significantly. After two sessions, the Schirmer test exhibited a decrease, and NIBUT increased, although these changes did not reach statistical significance. The curative effect was unrelated to sex, age, first onset, single disease, and other factors.

Conclusion: After treatment, the diameter of chalazions was reduced in 91.3% of the patients, and the area of the meibomian gland was significantly increased compared with that before treatment, which suggested that 2 OPT treatments at an interval of 1 week can improve the signs of adult patients in the non-acute infectious stage with chalazia.

Keywords: chalazions; conjunctival congestion; meibomian gland area; meibomian gland cyst; optimal pulse technology.

Grants and funding

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. The present study was funded by the Youth Scientific Research Fund of Guangzhou Aier Eye Hospital (no. G2022004).