Quorum sensing: cell-to-cell communication in Saccharomyces cerevisiae

Linbo Li; Yuru Pan; Shishuang Zhang; Tianyou Yang; Zhigang Li; Baoshi Wang; Haiyan Sun; Mingxia Zhang; Xu Li

doi:10.3389/fmicb.2023.1250151

Quorum sensing: cell-to-cell communication in Saccharomyces cerevisiae

Front Microbiol. 2023 Nov 23:14:1250151. doi: 10.3389/fmicb.2023.1250151. eCollection 2023.

Authors

Linbo Li¹, Yuru Pan¹, Shishuang Zhang¹, Tianyou Yang¹, Zhigang Li¹, Baoshi Wang¹, Haiyan Sun², Mingxia Zhang¹, Xu Li¹

Affiliations

¹ School of Life Sciences and Technology, Henan Institute of Science and Technology, Xinxiang, Henan, China.
² Hainan Key Laboratory of Tropical Microbe Resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan, China.

Abstract

Quorum sensing (QS) is one of the most well-studied cell-to-cell communication mechanisms in microorganisms. This intercellular communication process in Saccharomyces cerevisiae began to attract more and more attention for researchers since 2006, and phenylethanol, tryptophol, and tyrosol have been proven to be the main quorum sensing molecules (QSMs) of S. cerevisiae. In this paper, the research history and hotspots of QS in S. cerevisiae are reviewed, in particular, the QS system of S. cerevisiae is introduced from the aspects of regulation mechanism of QSMs synthesis, influencing factors of QSMs production, and response mechanism of QSMs. Finally, the employment of QS in adaptation to stress, fermentation products increasing, and food preservation in S. cerevisiae was reviewed. This review will be useful for investigating the microbial interactions of S. cerevisiae, will be helpful for the fermentation process in which yeast participates, and will provide an important reference for future research on S. cerevisiae QS.

Keywords: Saccharomyces cerevisiae; quorum sensing; quorum sensing molecules; quorum sensing system; response mechanism.

Publication types

Review

Grants and funding

This research was supported by the Science and Technology Program of Henan Province (222102110122), the Open Project Program of Key Laboratory of Feed Biotechnology, the Ministry of Agriculture and Rural Affairs of the People’s Republic of China (No. SUN01) Innovative Research Team (in Science and Technology) in University of Henan Province (22IRTSHN025), and China Agriculture Research System of Finance and Agriculture Ministry (CARS-11-HNSHY).