The first strain of monkeypox isolated in the Chinese Mainland and preserved at the National Pathogen Resource Center of China

Qiang Wei; Baoying Huang; Wei Huang; Jingdong Song; Li Mei; Li Zhao; Jing Yin; Juan Zhang; Wenling Wang; Fei Ye; Caiyun Li; Liling Bai; Yanhai Wang; Yao Deng; Bo Liu; Mengnan Jiang; Guizhen Wu; Jun Han; Hua Zhao; Hua Ling; Wenjie Tan; Jianjun Liu

doi:10.1016/j.imj.2022.11.003

The first strain of monkeypox isolated in the Chinese Mainland and preserved at the National Pathogen Resource Center of China

Infect Med (Beijing). 2022 Nov 19;1(4):288-291. doi: 10.1016/j.imj.2022.11.003. eCollection 2022 Dec.

Authors

Qiang Wei^{1

2}, Baoying Huang³, Wei Huang^{4

5}, Jingdong Song³, Li Mei^{1

2}, Li Zhao³, Jing Yin⁶, Juan Zhang⁷, Wenling Wang³, Fei Ye³, Caiyun Li⁶, Liling Bai⁷, Yanhai Wang³, Yao Deng³, Bo Liu², Mengnan Jiang^{1

2}, Guizhen Wu³, Jun Han³, Hua Zhao^{4

5}, Hua Ling^{4

5}, Wenjie Tan³, Jianjun Liu²

Affiliations

¹ National Pathogen Resource Center, Chinese Center for Disease Control and Prevention, Beijing, China.
² Chinese Center for Disease Control and Prevention, Beijing, China.
³ NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, China CDC, Beijing, China.
⁴ Chongqing Center for Disease Control and Prevention, Chongqing, China.
⁵ Chongqing Municipal Key Laboratory for High Pathogenic Microbes, Chongqing, China.
⁶ Nan'an Center for Disease Control and Prevention, Chongqing, China.
⁷ Nan'an People's Hospital, Chongqing, China.

Abstract

On September 16, 2022, the first imported monkeypox case was reported in the Chinese Mainland. Laboratory tests including nucleic acid detection were carried out in Chongqing Nan'an Centre for Disease Control and Prevention and Chongqing Center for Disease Control and Prevention. After that, monkeypox virus was isolated by the Institute for Viral Disease Control and Prevention and preserved at the National Pathogen Resource Center on September 18, 2022. The National Pathogen Resource Center shared the basic information of monkeypox virus strain, samples, biosafety, strain imaging, RT-PCR primers, and probes sequence timely to support the prevention and control of monkeypox epidemic and facilitate the scientific research on vaccine development, drug screening and evaluation of monkeypox virus in the future.

Keywords: Monkeypox; National Pathogen Resource Center (NPRC); Preservation; Sharing.