Association of dietary live microbe intake with abdominal aortic calcification in US adults: a cross-sectional study of NHANES 2013-2014

Xingwei Huo; Shanshan Jia; Xin Zhang; Lirong Sun; Xueting Liu; Lu Liu; Xianghao Zuo; Xiaoping Chen

doi:10.3389/fnut.2023.1267607

Association of dietary live microbe intake with abdominal aortic calcification in US adults: a cross-sectional study of NHANES 2013-2014

Front Nutr. 2023 Nov 24:10:1267607. doi: 10.3389/fnut.2023.1267607. eCollection 2023.

Authors

Xingwei Huo¹, Shanshan Jia¹, Xin Zhang¹, Lirong Sun^{1

2}, Xueting Liu¹, Lu Liu¹, Xianghao Zuo¹, Xiaoping Chen¹

Affiliations

¹ Department of Cardiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
² Second Department of Internal Medicine, Affiliated Hospital of Tibet University for Nationalities, Xianyang, Shaanxi, China.

Abstract

Object: To explore the potential association between dietary live microbe intake and abdominal aortic calcification (AAC).

Methods: We conducted a cross-section study based on the National Health and Nutrition Examination Survey (NHANES). We categorized the participants into three groups (low, medium, and high dietary intake of live microbes) according to Sanders's dietary live microbe classification system and participants' 24-h dietary recall data. AAC was quantified by using dual-energy X-ray absorptiometry (DXA) and diagnosed by using the Kauppila AAC-24 score system. The analyses utilized weighted logistic regression and weighted linear regression.

Results: A total of 2,586 participants were included. After the full adjustment for covariates, compared to participants with a low dietary live microbe intake, participants with a high dietary live microbe intake had a significantly lower risk of severe AAC (OR: 0.39, 95% CI: 0.22, 0.68, p = 0.003), and the AAC score was also significantly decreased (β:-0.53, 95% CI: -0.83, -0.23, p = 0.002).

Conclusion: In this study, more dietary live microbial intake was associated with lower AAC scores and a lower risk of severe AAC. However, more research is needed to verify this.

Keywords: NHANES; abdominal aortic calcification; cross-sectional study; dietary live microbes; food-gut-health axis.

Grants and funding

The authors declare financial support was received for the research, authorship, and/or publication of this article. This study was supported by the National Natural Science Foundation of China (Nos. 81900404 and 81970355).