Working from home during the COVID-19 pandemic. The role of physical activity to counteract the workers' oxidative stress. A pilot study

Federica Ghelli; Giulia Squillacioti; Valeria Bellisario; Samar El Sherbiny; Fulvia Guglieri; Giulia M Picone; Roberto Bono

doi:10.1177/20552076231218921

Working from home during the COVID-19 pandemic. The role of physical activity to counteract the workers' oxidative stress. A pilot study

Digit Health. 2023 Dec 6:9:20552076231218921. doi: 10.1177/20552076231218921. eCollection 2023 Jan-Dec.

Authors

Federica Ghelli¹, Giulia Squillacioti¹, Valeria Bellisario¹, Samar El Sherbiny¹, Fulvia Guglieri¹, Giulia M Picone², Roberto Bono¹

Affiliations

¹ Department of Public Health and Pediatrics, University of Turin, Torino, Italy.
² Clinical Biochemistry laboratory, AOU Città della Salute e della Scienza di Torino, Italy.

Abstract

Objective: Office workers spend typically more than two-thirds of their working time sitting and this negative behaviour could have been increased during the pandemic. Low levels of Physical Activity (PA) can have detrimental effects on health, well-being, and Quality of Life (QoL), as well as on the oxidative stress burden. Our aim was to evaluate the role of moderate PA remotely administered in modulating the bio-molecular profile and the QoL of a group of workers during the COVID-19 pandemic.

Methods: The 26 subjects recruited were sampled at the beginning of the study (T0), after 3 months of remotely administered training (T1), and 3 months after the suspension of the online workouts (T2). Each of the three times, subjects filled out a questionnaire and provided a spot urine sample for the quantification of oxidative stress (15-F2t-Isoprostane, Thiobarbituric Acid Reactive Substances (TBARS), and Total Antioxidant Power (TAP)) and inflammatory biomarkers (Interleukin (IL)-6 and IL-10).

Results: The PA administration resulted in a significant decrease in 15-F2t-Isoprostane (p = 0.02) and TAP (p = 0.019). A significant increase in TAP was observed between T1 and T2 (p = 0.044).

Conclusion: A PA-based health promotion strategy could be a valuable intervention in the working environment to promote the well-being of an ageing workforce, especially for white collars.

Keywords: exercise; inflammation; oxidative stress; psychological well-being; quality of life; working conditions.