The demand for sensitive and non-invasive sensors for monitoring glucose levels in sweat has grown considerably in recent years. This study presents the development of a wearable sensor for sweat glucose detection with ultrahigh sensitivity. The sensor was fabricated by embedding Au nanoparticles (AuNPs) and metal-organic gels (MOGs) on nickel foam (NF). A non-enzymatic electrocatalytic glucose sensor has been developed to combine the three-dimensional network of MOGs with more active sites favourable for glucose diffusion and the transfer of electrons from glucose to the electrode. These results show that the sensor has an ultrahigh sensitivity of 13.94 mA mM-1 cm-2, a linear detection range between 2 and 600 μM, and a lower detection limit as low as 1 μM (signal/noise = 3) with comparable accuracy and reliability under non-alkaline conditions to those of high-pressure ion chromatography (HPIC). Furthermore, a wearable sweat glucose sensor has been constructed by sputtering an Au conductive layer on a flexible polydimethylsiloxane (PDMS) substrate and coating it with Au@MOGs. Our work demonstrates that the combination of Au NPs and MOGs can enhance the sensitivity and activity of these materials, making them useful for electrocatalytic glucose monitoring with ultrahigh sensitivity.