Bacteriophage Taxonomy: A Continually Evolving Discipline

Methods Mol Biol. 2024:2734:27-45. doi: 10.1007/978-1-0716-3523-0_3.

Abstract

While taxonomy is an often underappreciated branch of science, it serves very important roles. Bacteriophage taxonomy has evolved from a discipline based mainly on morphology, characterized by the work of David Bradley and Hans-Wolfgang Ackermann, to the sequence-based approach that is taken today. The Bacterial Viruses Subcommittee of the International Committee on Taxonomy of Viruses (ICTV) takes a holistic approach to classifying prokaryote viruses by measuring overall DNA and protein similarity and phylogeny before making decisions about the taxonomic position of a new virus. The huge number of complete genomes being deposited with the National Center for Biotechnology Information (NCBI) and other public databases has resulted in a reassessment of the taxonomy of many viruses, and the future will see the introduction of new viral families and higher orders.

Keywords: DNA sequence homology; ICTV; Morphology; NCBI; Taxonomy.

MeSH terms

  • Bacteriophages* / genetics
  • Databases, Factual
  • Forecasting
  • Genome, Viral
  • Humans
  • Phylogeny
  • Viruses* / genetics