Relapsing polychondritis presenting with sero-negative limbic encephalitis

Clin Med (Lond). 2023 Nov;23(6):618-620. doi: 10.7861/clinmed.2023-0430.

Abstract

The presented case highlights a rare instance of relapsing polychondritis (RP) manifesting as seronegative limbic encephalitis, an uncommon neurological complication. A 70-year-old female patient with a history of RP-related inflammation, along with neuropsychiatric symptoms, was diagnosed through multidisciplinary collaboration. Swift administration of steroid therapy, followed by azathioprine, led to remarkable physical and cognitive recovery. This case emphasises the importance of a multidisciplinary approach in diagnosing and treating complex autoimmune disorders with neurological manifestations.

Keywords: MDT approach; limbic encephalitis; relapsing polychondritis.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Azathioprine
  • Female
  • Humans
  • Limbic Encephalitis* / complications
  • Limbic Encephalitis* / etiology
  • Polychondritis, Relapsing* / complications
  • Polychondritis, Relapsing* / diagnosis

Substances

  • Azathioprine