Breath biomarkers in Non-Carcinogenic diseases

Clin Chim Acta. 2024 Jan 1:552:117692. doi: 10.1016/j.cca.2023.117692. Epub 2023 Dec 7.

Abstract

The analysis of volatile organic compounds (VOCs) from human matrices like breath, perspiration, and urine has received increasing attention from academic and medical researchers worldwide. These biological-borne VOCs molecules have characteristics that can be directly related to physiologic and pathophysiologic metabolic processes. In this work, gathers a total of 292 analytes that have been identified as potential biomarkers for the diagnosis of various non-carcinogenic diseases. Herein we review the advances in VOCs with a focus on breath biomarkers and their potential role as minimally invasive tools to improve diagnosis prognosis and therapeutic monitoring.

Keywords: Biomarkers; Breath Sampling; Exhaled Breath; Non-Carcinogenic Diseases; VOCs; Volatile Organic Compounds.

Publication types

  • Review

MeSH terms

  • Biomarkers
  • Breath Tests*
  • Humans
  • Volatile Organic Compounds*

Substances

  • Biomarkers
  • Volatile Organic Compounds