U structured network with three encoding paths for breast tumor segmentation

Sci Rep. 2023 Dec 7;13(1):21597. doi: 10.1038/s41598-023-48883-y.

Abstract

Breast ultrasound segmentation remains challenging because of the blurred boundaries, irregular shapes, and the presence of shadowing and speckle noise. The majority of approaches stack convolutional layers to extract advanced semantic information, which makes it difficult to handle multiscale issues. To address those issues, we propose a three-path U-structure network (TPUNet) that consists of a three-path encoder and an attention-based feature fusion block (AFF Block). Specifically, instead of simply stacking convolutional layers, we design a three-path encoder to capture multiscale features through three independent encoding paths. Additionally, we design an attention-based feature fusion block to weight and fuse feature maps in spatial and channel dimensions. The AFF Block encourages different paths to compete with each other in order to synthesize more salient feature maps. We also investigate a hybrid loss function for reducing false negative regions and refining the boundary segmentation, as well as the deep supervision to guide different paths to capture the effective features under the corresponding receptive field sizes. According to experimental findings, our proposed TPUNet achieves more excellent results in terms of quantitative analysis and visual quality than other rival approaches.

MeSH terms

  • Animals
  • Breast Neoplasms* / diagnostic imaging
  • Female
  • Humans
  • Image Processing, Computer-Assisted
  • Mammary Neoplasms, Animal*
  • Semantics
  • Ultrasonography, Mammary