Idiopathic left-sided ovarian vein thrombosis in a post-menopausal woman

BMJ Case Rep. 2023 Dec 7;16(12):e257856. doi: 10.1136/bcr-2023-257856.

Abstract

Ovarian vein thrombosis (OVT) is a rare thromboembolic condition largely involving the right ovarian vein. Risk factors include pregnancy/ peripartum period, oestrogen therapy, recent surgery or hospitalisation, malignancy, pelvic inflammatory diseases, and thrombophilia; OVT without risk factors is considered idiopathic. We present a rare case of idiopathic left-sided OVT in a post-menopausal woman in her 60s with insignificant past medical history and no identifiable risk factors. She presented with isolated left -lower -quadrant abdominal pain ultimately found to have OVT on computed tomography (CT) scan and confirmed with magnetic resonance imaging (MRI). The patient was initially treated with low-molecular-weight heparin and then transitioned to apixaban. She remained symptom-free at 3-month follow-up. Five previous cases of idiopathic left-sided OVT have been reported to-date, but this is the first case in a postmenopausal woman that has not been associated with hypercoagulable risk factors nor further thromboembolic complications.

Keywords: Haematology (incl blood transfusion); Malignant and Benign haematology; Pregnancy; Thrombosis; Venous thromboembolism.

Publication types

  • Case Reports

MeSH terms

  • Abdominal Pain / etiology
  • Female
  • Humans
  • Ovary / blood supply
  • Ovary / diagnostic imaging
  • Postmenopause
  • Pregnancy
  • Thrombophilia* / complications
  • Thrombophilia* / drug therapy
  • Tomography, X-Ray Computed / methods
  • Vena Cava, Inferior
  • Venous Thrombosis* / complications
  • Venous Thrombosis* / diagnostic imaging
  • Venous Thrombosis* / drug therapy