A near-infrared fluorescent probe for rapid and on-site detection of sulfur dioxide derivative in biological, food and environmental systems

Zhuye Shang; Miaomiao Wu; Qingtao Meng; Yang Jiao; Zhiqiang Zhang; Run Zhang

doi:10.1016/j.jhazmat.2023.133165

A near-infrared fluorescent probe for rapid and on-site detection of sulfur dioxide derivative in biological, food and environmental systems

J Hazard Mater. 2024 Mar 5:465:133165. doi: 10.1016/j.jhazmat.2023.133165. Epub 2023 Dec 2.

Authors

Zhuye Shang¹, Miaomiao Wu², Qingtao Meng³, Yang Jiao⁴, Zhiqiang Zhang⁵, Run Zhang⁶

Affiliations

¹ School of Chemical Engineering, University of Science and Technology Liaoning, Anshan, Liaoning 114051, PR China.
² Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD 4072, Australia.
³ School of Chemical Engineering, University of Science and Technology Liaoning, Anshan, Liaoning 114051, PR China; Key Laboratory of Functional Materials in Universities of Liaoning Province, University of Science and Technology Liaoning, Anshan, Liaoning 114051, PR China. Electronic address: qtmeng@ustl.edu.cn.
⁴ State Key Laboratory of Fine Chemicals, School of Chemistry, Dalian University of Technology, Dalian 116024, China.
⁵ School of Chemical Engineering, University of Science and Technology Liaoning, Anshan, Liaoning 114051, PR China. Electronic address: zzq@ustl.edu.cn.
⁶ Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD 4072, Australia. Electronic address: r.zhang@uq.edu.au.

PMID: 38061127
DOI: 10.1016/j.jhazmat.2023.133165

Abstract

Emission of toxic gaseous sulfur dioxide (SO₂) and its derivative bisulfite (HSO₃^-) from various industrial applications, like food processing, transportation, and the coking process, has raised substantial concerns regarding environmental quality and public health. The probes for specific and sensitive detection of SO₂ derivatives plays an essential role in their regulation, and ultimately mitigating their environmental and health implications, but the one that can detect SO₂ derivatives onsite by end users remains limited. Herein, we report a new near-infrared fluorescence probe (SL) for rapid and onsite detection of SO₂ derivative, HSO₃^- in industrial wastewater, food samples and for sensing its interaction with biological organisms. The SL is developed through coupling of quinolinium and coumarin moiety through an electron deficit CC bond that can specifically react with HSO₃^- via a Michael addition. By recording the blue shift of absorption and emission spectra, SL can sensitively detect HSO₃^- (limit of detection, 38 nM) in aqueous solution within 40 s SL is biocompatible, can be used for evaluating toxicity of SO₂ derivatives in living organisms. The preparation of SL-stained test paper allows the colorimetric/fluorometric analysis for quantification of HSO₃^- onsite in food, river and coking wastewater samples using a smartphone. The successful development of SL not only provides a new tool to investigate HSO₃^- in biological, food and environmental systems, but also potentially promotes the application of fluorescence technique for rapid and onsite analysis of real-world samples by end users.

Keywords: Bisulfite responsive probe; Environmental analysis; Near-infrared fluorescence; Smartphone-based technique.

MeSH terms

Fluorescent Dyes* / chemistry
Fluorometry
Food
HeLa Cells
Humans
Sulfur Dioxide* / analysis
Wastewater

Substances

Fluorescent Dyes
Sulfur Dioxide
Wastewater