Mapping morphogenesis and mechanics in embryo models

Zong-Yuan Liu; Vikas Trivedi; Idse Heemskerk

doi:10.1038/s41592-023-02079-4

Mapping morphogenesis and mechanics in embryo models

Nat Methods. 2023 Dec;20(12):1859-1862. doi: 10.1038/s41592-023-02079-4.

Authors

Zong-Yuan Liu¹, Vikas Trivedi^{2

3}, Idse Heemskerk^{4

5

6

7

8}

Affiliations

¹ Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, USA.
² EMBL Barcelona, Barcelona, Spain.
³ EMBL Heidelberg, Developmental Biology Unit, Heidelberg, Germany.
⁴ Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, USA. iheemske@umich.edu.
⁵ Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA. iheemske@umich.edu.
⁶ Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, MI, USA. iheemske@umich.edu.
⁷ Center for Cell Plasticity and Organ Design, University of Michigan Medical School, Ann Arbor, MI, USA. iheemske@umich.edu.
⁸ Department of Physics, University of Michigan, Ann Arbor, MI, USA. iheemske@umich.edu.

Abstract

Recent methodological advances in measurements of geometry and forces in the early embryo and its models are enabling a deeper understanding of the complex interplay of genetics, mechanics and geometry during development.

Grants and funding

R35 GM138346/GM/NIGMS NIH HHS/United States