Relief of nocturnal neuropathic pain with the use of cannabis in a patient with Fabry disease

Martina Bon; Andrea Dardis; Maurizio Scarpa; Annalisa Sechi

doi:10.1016/j.ymgmr.2023.101010

Relief of nocturnal neuropathic pain with the use of cannabis in a patient with Fabry disease

Mol Genet Metab Rep. 2023 Oct 6:37:101010. doi: 10.1016/j.ymgmr.2023.101010. eCollection 2023 Dec.

Authors

Martina Bon¹, Andrea Dardis¹, Maurizio Scarpa¹, Annalisa Sechi¹

Affiliation

¹ Regional Coordinating Center for Rare Diseases, University Hospital of Udine, Udine, Italy.

Abstract

Neuropathic pain is one of the most invalidating symptoms in patients with Fabry disease (FD), affecting their quality of life, it is linked to small fiber neuropathy and it may not respond to available disease specific treatments. We report the case of a 32 years old man with classic FD and severe neuropathic pain who, after the failure of several standard pharmaceutical approaches, was treated with medical cannabis with relief of nocturnal pain and sleep improvement.

Keywords: Fabry disease; Medical Cannabis; Neuropathic pain; Pain treatment; Small fiber neuropathy.

Publication types

Case Reports