Printed circuit boards: system automation and alternative matrix for biosensing

Supratim Mahapatra; Rohini Kumari; Pranjal Chandra

doi:10.1016/j.tibtech.2023.11.002

Printed circuit boards: system automation and alternative matrix for biosensing

Trends Biotechnol. 2023 Dec 4:S0167-7799(23)00324-4. doi: 10.1016/j.tibtech.2023.11.002. Online ahead of print.

Authors

Supratim Mahapatra¹, Rohini Kumari¹, Pranjal Chandra²

Affiliations

¹ Laboratory of Bio-Physio Sensors and Nanobioengineering, School of Biochemical Engineering, Indian Institute of Technology (BHU), Varanasi, Uttar Pradesh 221005, India.
² Laboratory of Bio-Physio Sensors and Nanobioengineering, School of Biochemical Engineering, Indian Institute of Technology (BHU), Varanasi, Uttar Pradesh 221005, India. Electronic address: pranjal.bce@iitbhu.ac.in.

PMID: 38052681
DOI: 10.1016/j.tibtech.2023.11.002

Abstract

Circuit integration has revolutionized the diagnostic sector by improving the sensing ability and rapidity of biosensors. Bioelectronics has led to the development of point-of-care (PoC) devices, offering superior performance compared with conventional biosensing systems. These devices have lower production costs, are smaller, and have greater reproducibility, enabling the construction of compact sensing modules. Flexible upgrades to the fabrication pattern of the printed circuit board (PCB) remains the most reliable and consistent means so far, offering portability, wearability, a lower detection limit, and smart output integration to these devices. This review summarizes the advances in PCB technology for biosensing devices for introducing automation and their emerging application as an alternative matrix material for detecting various analytes.

Keywords: PCB technology; alternative sensing matrices; automation; bioelectronics; miniaturization.

Publication types

Review