Recent advances of responsive scaffolds in bone tissue engineering

Tongyu Zhu; Hongbo Zhou; Xiaojing Chen; Yuanjing Zhu

doi:10.3389/fbioe.2023.1296881

Recent advances of responsive scaffolds in bone tissue engineering

Front Bioeng Biotechnol. 2023 Nov 17:11:1296881. doi: 10.3389/fbioe.2023.1296881. eCollection 2023.

Authors

Tongyu Zhu^#¹, Hongbo Zhou^#¹, Xiaojing Chen¹, Yuanjing Zhu¹

Affiliation

¹ Hunan Clinical Research Center of Oral Major Diseases and Oral Health, Xiangya Stomatological Hospital, Xiangya School of Stomatology, Central South University, Changsha, Hunan, China.

^# Contributed equally.

Abstract

The investigation of bone defect repair has been a significant focus in clinical research. The gradual progress and utilization of different scaffolds for bone repair have been facilitated by advancements in material science and tissue engineering. In recent times, the attainment of precise regulation and targeted drug release has emerged as a crucial concern in bone tissue engineering. As a result, we present a comprehensive review of recent developments in responsive scaffolds pertaining to the field of bone defect repair. The objective of this review is to provide a comprehensive summary and forecast of prospects, thereby contributing novel insights to the field of bone defect repair.

Keywords: bone tissue engineering; inflammatory; responsive scaffolds; stimuli; targeted drug delivery.

Publication types

Review

Grants and funding

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by Natural Science Foundation for Youth of Hunan Province of China (Grant No. 2021JJ40909); Fundamental Research Funds for the Central Universities of Central South University (Grant No. 1053320213327).