Sleep-related breathing disorder (central sleep apnoea) improved coincidentally by medical therapy with fumarates (dimethyl fumarate)

Abdulmajeed M Albadi; Mana M Alshahrani; Riyad O Allehebi

doi:10.7573/dic.2023-6-3

Sleep-related breathing disorder (central sleep apnoea) improved coincidentally by medical therapy with fumarates (dimethyl fumarate)

Drugs Context. 2023 Nov 23:12:2023-6-3. doi: 10.7573/dic.2023-6-3. eCollection 2023.

Authors

Abdulmajeed M Albadi^{1

2}, Mana M Alshahrani¹, Riyad O Allehebi¹

Affiliations

¹ Department of Pulmonary Medicine, Sleep Medicine Unit, King Fahad Medical City, Riyadh, Saudi Arabia.
² Prince Mohammad bin Abdulaziz Medical City, Aljouf, Saudi Arabia.

Abstract

Central sleep apnoea (CSA) is a sleep disorder characterized by the repeated cessation or reduction of both airflow and ventilatory effort when sleeping. Individuals with central breathing disorders have difficulty in receiving appropriate medical treatment. In this article, we describe a case study of a 31-year-old woman known to have multiple sclerosis and concomitant severe CSA. She received the medication dimethyl fumarate for the treatment of multiple sclerosis, and her CSA significantly improved to mild CSA after the treatment.

Keywords: central sleep apnoea; hypoventilation; multiple sclerosis; sleep.

Publication types

Case Reports