Repetitive transcranial magnetic stimulation (rTMS) as a tool for cognitive enhancement in healthy adults: a review study

Med Biol Eng Comput. 2024 Mar;62(3):653-673. doi: 10.1007/s11517-023-02968-y. Epub 2023 Dec 4.

Abstract

As human beings, we have always sought to expand on our abilities, including our cognitive and motor skills. One of the still-underrated tools employed to this end is repetitive transcranial magnetic stimulation (rTMS). Until recently, rTMS was almost exclusively used in studies with rehabilitation purposes. Only a small strand of literature has focused on the application of rTMS on healthy people with the aim of enhancing cognitive abilities such as decision-making, working memory, attention, source memory, cognitive control, learning, computational speed, risk-taking, and impulsive behaviors. It, therefore, seems that the findings in this particular field are the indirect results of rehabilitation research. In this review paper, we have set to investigate such studies and evaluate the rTMS effectuality in terms of how it improves the cognitive skills in healthy subjects. Furthermore, since the most common brain site used for rTMS protocols is the dorsolateral prefrontal cortex (DLPFC), we have added theta burst stimulation (TBS) wave patterns that are similar to brain patterns to increase the effectiveness of this method. The results of this study can help people who have high-risk jobs including firefighters, surgeons, and military officers with their job performance.

Keywords: Classification; Cognitive enhancement; Dorso-lateral prefrontal cortex (DLPFC); Electroencephalography (EEG); Major depressive disorder (MDD); Repetitive transcranial magnetic stimulation (rTMS).

Publication types

  • Review

MeSH terms

  • Adult
  • Brain
  • Cognition
  • Electroencephalography* / methods
  • Humans
  • Prefrontal Cortex / physiology
  • Transcranial Magnetic Stimulation* / methods
  • Treatment Outcome