Medication reconciliation on admission in paediatric chronic patients: A multicentre study

An Pediatr (Engl Ed). 2023 Dec;99(6):376-384. doi: 10.1016/j.anpede.2023.11.008. Epub 2023 Nov 29.

Abstract

Introduction: Medication reconciliation (MC) is one of the main strategies to reduce medication errors in care transitions. In Spain, several guidelines have been published with recommendations for the implementation and development of MC aimed at the adult population, although paediatric patients are not included. In 2018, a study was carried out that led to the subsequent publication of a document with criteria for selecting paediatric patients in whom CM should be prioritised.

Objectives: To describe the characteristics of paediatric patients most likely to suffer from errors of reconciliation (EC), to confirm whether the results of a previous study can be extrapolated.

Methodology: Prospective, multicentre study of paediatric inpatients. We analysed the CE detected during the performance of the CM on admission. The best possible pharmacotherapeutic history of the patient was obtained using different sources of information and confirmed by an interview with the patient/caregiver.

Results: 1043 discrepancies were detected, 544 were identified as CD, affecting 317 patients (43%). Omission of a drug was the most common error (51%). The majority of CD were associated with drugs in groups A (31%), N (23%) and R (11%) of the ATC classification. Polymedication and onco-haematological based disease were the risk factors associated with the presence of CD with statistical significance.

Conclusions: The findings of this study allow prioritisation of CM in a specific group of paediatric patients, favouring the efficiency of the process. Onco-haematological patients and polymedication are confirmed as the main risk factors for the appearance of CD in the paediatric population.

Keywords: Care transitions; Conciliación de la medicación; Discrepancia; Discrepancy; Errores de medicación; Medication errors; Medication reconciliation; Paediatrics; Pediatría; Transiciones asistenciales.

Publication types

  • Multicenter Study

MeSH terms

  • Child
  • Humans
  • Medication Errors / prevention & control
  • Medication Reconciliation* / methods
  • Patient Admission*
  • Prospective Studies
  • Risk Factors