Patient-specific warning of epileptic seizure upon shapelets features

Heliyon. 2023 Nov 17;9(11):e22431. doi: 10.1016/j.heliyon.2023.e22431. eCollection 2023 Nov.

Abstract

Epilepsy is an intractable chronic neurological disease attached to extensive attention. Due to the fact that unpredictable seizure attacks result in serious physical injuries, early warning before seizure occurrence can help patients to get timely treatment and intervention. This paper presents a novel patient-specific method to predict epileptic seizures by learning shapelets of scalp electroencephalogram (EEG) signals recorded from different channels. In the proposed method, EEG signals are preprocessed to raise the Signal to Noise Rate (SNR). Multichannel shapelets space is constructed by the learning-near-to-optimal shapelets method. EEG signals are converted to distance matrices by projecting them on the shapelets' space. Bi-LSTM, SVM, CNN, and an ensemble of them are used to classify the feature set. Based on the prediction results then raise alarms. The proposed methodology is applied to the CHB-MIT scalp EEG dataset of 10 cases. The proposed method achieves a sensitivity of 91.33% and a false prediction rate of 0.16 h-1.

Keywords: Bi-LSTM; CNN; EEG; Epileptic seizure prediction; Shapelets.