Advances in treatment planning and management for the safety and accuracy of lung stereotactic body radiation therapy using proton pencil beam scanning: Simulation, planning, quality assurance, and delivery recommendations

Minglei Kang; J Isabelle Choi; Kevin Souris; Jun Zhou; Gang Yu; Annemarie F Shepherd; Nitin Ohri; Stanislav Lazarev; Liyong Lin; Haibo Lin; Charles B Simone

Advances in treatment planning and management for the safety and accuracy of lung stereotactic body radiation therapy using proton pencil beam scanning: Simulation, planning, quality assurance, and delivery recommendations

J Radiosurg SBRT. 2023;9(1):53-62.

Authors

Minglei Kang¹, J Isabelle Choi^{1

2}, Kevin Souris³, Jun Zhou⁴, Gang Yu¹, Annemarie F Shepherd^{1

2}, Nitin Ohri^{1

5}, Stanislav Lazarev^{1

6}, Liyong Lin⁴, Haibo Lin^{1

2

5}, Charles B Simone^{1

2}

Affiliations

¹ New York Proton Center, New York, NY, USA.
² Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, New York NY, USA.
³ IBA, Louvain-La-Neuve, Belgium.
⁴ Emory University, Department of Radiation Oncology, Atlanta, GA, USA|.
⁵ Montefiore Medical Center, Department of Radiation Oncology, Bronx, NY, USA.
⁶ Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, New York, NY, USA.

PMID: 38029008
PMCID: PMC10681141

Abstract

This study presents the clinical experiences of the New York Proton Center in employing proton pencil beam scanning (PBS) for the treatment of lung stereotactic body radiation therapy. It encompasses a comprehensive examination of multiple facets, including patient simulation, delineation of target volumes and organs at risk, treatment planning, plan evaluation, quality assurance, and motion management strategies. By sharing the approaches of the New York Proton Center and providing recommendations across simulation, treatment planning, and treatment delivery, it is anticipated that the valuable experience will be provided to a broader proton therapy community, serving as a useful reference for future clinical practice and research endeavors in the field of stereotactic body proton therapy for lung tumors.

Keywords: Proton pencil beam scanning; lung SBRT; motion management; recommendations; stereotactic.