Rise of the (possible) resistance: a review of susceptibility patterns for nontyphoidal Salmonella enterica in Nebraska

Shawnalyn W Sunagawa; Catherine Christopherson; Scott J Bergman; Molly M Miller; Mackenzie R Keintz; Taylor A Wahlig; Paul Fey; Trevor C Van Schooneveld

doi:10.1017/ash.2023.464

Rise of the (possible) resistance: a review of susceptibility patterns for nontyphoidal Salmonella enterica in Nebraska

Antimicrob Steward Healthc Epidemiol. 2023 Oct 23;3(1):e181. doi: 10.1017/ash.2023.464. eCollection 2023.

Authors

Shawnalyn W Sunagawa^{1

2}, Catherine Christopherson², Scott J Bergman^{1

2}, Molly M Miller¹, Mackenzie R Keintz³, Taylor A Wahlig⁴, Paul Fey⁴, Trevor C Van Schooneveld³

Affiliations

¹ Department of Pharmaceutical and Nutrition Care, Nebraska Medicine, Omaha, NE, USA.
² College of Pharmacy, University of Nebraska Medicine Center, Omaha, NE, USA.
³ Division of Infectious Diseases, University of Nebraska Medical Center, Omaha, NE, USA.
⁴ Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.

Abstract

Our institution sought to evaluate our antimicrobial stewardship empiric treatment recommendations for Salmonella. Results from 36 isolates demonstrated reduced susceptibilities to fluoroquinolones with 1 isolate susceptible only to ceftriaxone. Analysis supports the current recommendation of empiric ceftriaxone therapy for severe infection and updated recommendation for sulfamethoxazole-trimethoprim in non-severe infections.