Premorbid weight in pulmonary arterial hypertension

Pulm Circ. 2023 Nov 21;13(4):e12308. doi: 10.1002/pul2.12308. eCollection 2023 Oct.

Abstract

Relationships between obesity and outcomes in pulmonary arterial hypertension (PAH) are complex. Previous work suggested obesity, occurring alongside PAH, may be associated with better survival. In our work, we suggest obesity prior to PAH development is associated with worse survival. This may add a novel temporal element to the "obesity-paradox."

Keywords: epidemiology; obesity; pulmonary arterial hypertension; social determinants of lung health and disease.