Vertebral coccidioidomycosis with mechanical instability treated solely with antifungals: A case report

Sergio Charles-Lozoya; Gibran Ruíz-Zenteno; María E Lizcano-Martínez; Héctor Cobos-Aguilar; Joél León-Ruíz; Jesús Domínguez-Delgado

doi:10.1016/j.mmcr.2023.100615

Vertebral coccidioidomycosis with mechanical instability treated solely with antifungals: A case report

Med Mycol Case Rep. 2023 Nov 13:42:100615. doi: 10.1016/j.mmcr.2023.100615. eCollection 2023 Dec.

Authors

Sergio Charles-Lozoya^{1

2}, Gibran Ruíz-Zenteno¹, María E Lizcano-Martínez¹, Héctor Cobos-Aguilar², Joél León-Ruíz¹, Jesús Domínguez-Delgado¹

Affiliations

¹ Health Science Division, Unit of Spine Orthopedic Surgery, Hospital de Traumatología y Ortopedia No. 21, Instituto Mexicano del Seguro Social (IMSS), Av. José Ma. Pino Suárez y Juan Ignacio Ramón s/n, Centro, 64300, Monterrey, NL., Mexico.
² Health Science Division, Vice-rectory of Health Sciences, Universidad de Monterrey, Av. Ignacio Morones Prieto 4500 Pte.col. Jesus M. Garza, 66238, San Pedro Garza García, N.L., Mexico.

Abstract

Surgical treatment of vertebral coccidioidomycosis presents a challenge, with an unpredictable course and uncertain results. We present a 52-year-old man with disseminated infection due to coccidioidomycosis in the thoracolumbar spine, with vertebral instability, and deferral surgical treatment due to SARS-CoV-2 contingency. Treatment with itraconazole was initiated, followed by liposomal amphotericin B and fluconazole due to a relapse. The patient was discharged long-term with voriconazole. The axial pain improved without neurological deficits. Surgical treatment was not required. 2012 Elsevier Ltd. All rights reserved.

Keywords: Antifungals; Coronavirus infections; Fungi; Osteomyelitis; Spine; Surgery.

Publication types

Case Reports