Metastatic Melanoma Invading the Minor Duodenal Papilla in a Patient With Pancreas Divisum Causing Acute Recurrent Pancreatitis: A Case Report

Cureus. 2023 Oct 23;15(10):e47543. doi: 10.7759/cureus.47543. eCollection 2023 Oct.

Abstract

Metastasis to the gastrointestinal (GI) tract should always be a consideration when melanoma, particularly metastatic disease, is diagnosed. While metastasis to the small intestine is common, given its rich blood supply, metastasis to the pancreatic ducts is extremely rare. In patients with pancreatic divisum, disease spread to the minor papilla can greatly increase the chance of developing pancreatitis due to the potential for increased pancreatic intraductal pressure. We present one unique case of metastatic melanoma to the minor duodenal papilla causing pancreatitis.

Keywords: ampulla; endoscopic approach; endoscopic ultrasound (eus); ercp; melanoma; pancreas divisum; pancreatitis; recurrent pancreatitis.

Publication types

  • Case Reports