Short-term efficacy of stenting as a rescue therapy for acute atherosclerotic occlusion in anterior cerebral circulation

Jianyi Wang; Suhang Shang; Wanghuan Dun; Chen Chen; Fan Gao; Jia Yu; Jianfeng Han; Fude Liu

doi:10.3389/fneur.2023.1238998

Short-term efficacy of stenting as a rescue therapy for acute atherosclerotic occlusion in anterior cerebral circulation

Front Neurol. 2023 Nov 1:14:1238998. doi: 10.3389/fneur.2023.1238998. eCollection 2023.

Authors

Jianyi Wang¹, Suhang Shang¹, Wanghuan Dun², Chen Chen¹, Fan Gao³, Jia Yu¹, Jianfeng Han¹, Fude Liu¹

Affiliations

¹ Department of Neurology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shanxi, China.
² Department of Rehabilitation, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shanxi, China.
³ Clinical Research Center, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shanxi, China.

Abstract

Purpose: The study aimed to explore the efficacy and safety of the Neuroform EZ stent in treating acute anterior circulation large artery occlusion.

Methods: The clinical data of 42 consecutive patients with acute anterior circulation large atherosclerotic occlusion who were treated with the Neuroform EZ stent from January 2018 to August 2019 in our stroke care center, including baseline characteristics, images, therapeutic condition, and follow-up data were retrospectively analyzed.

Results: There were 42 mechanical thrombectomy (MT) failure cases of intracranial atherosclerotic stenosis with rescue Neuroform EZ stent implantation, of which 78.6% (33/42) had a good prognosis and 88.1% (37/42) showed no re-stenosis at follow-up. The average time from puncture to recanalization is 79.50 ± 14.19 min. The successful rate of intraoperative stent release is 97.6%, while there is one case of stent displacement, three cases of thrombus escape, and six cases of hemorrhage.

Conclusion: Rescue therapy of the Neuroform EZ stent for acute anterior circulation large atherosclerotic occlusion can archive good short-term imaging and clinical results, while long-term follow-up is still needed to verify.

Keywords: Neuroform EZ stent; acute ischemic stroke; atherosclerosis; efficacy; endovascular therapy (EVT); rescue therapy.

Grants and funding

This study was funded by the Shanxi Provincial Key Research and Development Project (2021SF-059) and the Natural Science Foundation of Shaanxi Province (2019JQ-565).