Primary Tracheobronchial Amyloidosis Presenting with an Upper Airway Obstruction

Zekewos Demissie; Nahom Zemedkun; Abraham Demile; Berhanu Nega; Yonas Bekuretsion; Bisrat Getachew; Bethelhem Berhanu

doi:10.2147/IMCRJ.S438379

Primary Tracheobronchial Amyloidosis Presenting with an Upper Airway Obstruction

Int Med Case Rep J. 2023 Nov 17:16:757-761. doi: 10.2147/IMCRJ.S438379. eCollection 2023.

Authors

Zekewos Demissie¹, Nahom Zemedkun¹, Abraham Demile¹, Berhanu Nega², Yonas Bekuretsion³, Bisrat Getachew⁴, Bethelhem Berhanu⁵

Affiliations

¹ Department of Internal Medicine, Lancet General Hospital, Addis Ababa, Ethiopia.
² Department of Surgery, Division of Cardiothoracic Surgery, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
³ Department of Pathology, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
⁴ Department of Otolaryngology, Head and Neck Surgery, St. Paul Millennium Medical College, Addis Ababa, Ethiopia.
⁵ Department of Radiology, St. Paul Millennium Medical College, Addis Ababa, Ethiopia.

Abstract

This is a case of localized primary tracheobronchial amyloidosis in a patient who presented with upper airway obstruction. Tracheobronchial amyloidosis is a type of localized bronchopulmonary amyloidosis that is frequently overlooked. It involves the deposition of amyloid protein on the tracheal and bronchial tissue, leading to progressive tracheal stenosis and airway obstruction that can be seen on imaging as a tracheal mass. Because of its significant diagnostic difficulty and therapeutic conundrum, it ought to be considered in the differential diagnosis of upper airway symptoms with an unknown etiology.

Keywords: tracheal mass; tracheobronchial amyloidosis; upper airway obstruction.

Publication types

Case Reports

Grants and funding

There is no funding to report.